The skin is colored by a blend of pigments, which form part of a complex and highly regulated process. Pigmentary defects normally present with dyschromia and can be caused by genetic defects, systemic disease, inflammatory processes, metabolic defects, infections, tumors, or toxic or iatrogenic causes. This atlas is an extensive text written by key opinion leaders within dermatology, it has a comprehensive format that guides the reader through the epidemiology, pathophysiology, diagnosis, treatment, and differential diagnosis of both common and rare pigmentary disorders. It illustrates the diagnosis and recognition of pigmentary disorders with a wide range of images. Thierry Passeron, MD, PhD, is a Professor of Dermatology at the University of Hospital of Nice, France. After his medical training Professor Passeron specialized in Dermatology in Nice University Hospital. From 2005 to 2007, he worked in the laboratory of Dr Vincent J Hearing at the National Institute of Health, National Cancer Institute, Bethesda, US, and characterized the role of SOX9 in melanocytes and in melanoma. Since 2010, he is full Professor of Dermatology at the University Hospital of Nice, France. Professor Passeron also heads the laboratory INSERM U1065 team 12, C3M, dedicated to the study of molecular mechanisms involved in pigmentation and melanoma and the University laser center. Currently, he has four international patents and more than 150 publications in scientific journals (h-index 30). His fields of research include pigmentary disorders, melanoma, and lasers.
Revolutionary changes in medical imaging have enormously improved the ability to detect structural and functional organ alterations early. Imaging is becoming an essential tool - in association with hormonal assays - for the diagnosis and management of endocrine disorders. New contrast media and their application to ultrasounds, as well as the opportunity to merge images acquired by functional/metabolic and traditional techniques, allow characterization of key features of identified lesions. Some radiological techniques such as ultrasonography, CT, and MRI are now available in operating rooms, thus supporting a diagnostic and therapeutic approach to endocrine diseases. In this new book, distinguished experts have contributed concise and well-illustrated chapters to describe pathognomonic features of several benign and malignant diseases affecting endocrine glands. They review the main advantages and disadvantages of each diagnostic technique along with indications for selecting a method. As a special feature, online videos of dynamic diagnostic and therapeutic procedures are available. Imaging in Endocrine Disorders is a must read and valuable reference for all professionals dealing with endocrine disorders, including internists and general practitioners who must manage the essential diagnostic workup.
This book summarizes the current state of movement disorder management and the role of surgical therapies as an alternative to medication. Following a chapter on the history of movement disorder surgery, leaders in their fields describe the pathophysiology, functional neuroanatomy, clinical presentation, and medical management of Parkinsons disease, dystonia, and essential tremor. This is followed by chapters on the spectrum of movement disorder surgery itself, from the lesioning procedures of radiofrequency ablation, stereotactic radiosurgery, and high-frequency ultrasound to the modulatory procedures of asleep, image-guided deep brain stimulation (DBS) and awake, microelectrode-guided DBS. The final chapters focus on closed-loop DBS, drug-delivery, gene therapy, and other emerging neurosurgical therapies, highlighting long-standing experimental strategies that are reaching exciting phases of clinical translation. This volume is a valuable tool for accessing the wide spectrum of concepts that currently define this dynamic field.
Get the tools you need to evaluate, diagnose, and treat patients with neurogenic communication disorders! Introduction to Neurogenic Communication Disorders, 8th Edition provides a solid foundation in the neurology of communication, as well as the causes, symptoms, diagnosis, assessment, and management of commonly encountered neurogenic communication disorders in adults. A concise, evidence-based approach shows how to measure and treat abnormalities such as aphasia, dysarthria, right-hemisphere syndrome, and traumatic brain injury syndrome. This edition is updated with new coverage of laboratory tests, blast-related injuries to the head, and medications for dementia. Created by neurogenic communication disorders educator Robert H. Brookshire and continued by Malcolm R. McNeil, this bestselling text will enhance your skills in the rehabilitation of clients with neurogenic communication disorders. A clear, concise approach makes complex material easy to follow and understand. Clinical vignettes show how to apply principles to practice and illustrate how patients are evaluated and treated. Thought questions at the end of each chapter are based on realistic scenarios and challenge you to assess your understanding, think critically, and apply information to clinical situations. Suggested answers are included in the appendix. Clinically relevant sidebars include related facts, information, and tips for recall or therapy. More than 200 photographs and images include anatomic illustrations, scans using various brain imaging techniques, and examples of assessment tests. Evidence-based practice is reinforced by the use of scientific, evidence-based rationales to support the effectiveness of treatment approaches. Student-friendly features enhance learning with chapter outlines, critical thinking exercises, medical protocols, sample paperwork, patient transcripts, commonly used medical abbreviations, and a glossary with definitions of key vocabulary. General Concepts summary points highlight the most important material in each chapter. NEW content on closed-head injuries as a consequence of blast injury is included in the Traumatic Brain Injury chapter, addressing a pathophysiology often found in Iraq and Afghanistan war veterans. UPDATED content includes new information on medications for treatment of persons with dementia, the latest laboratory tests for neurologic assessment, and the most current cognitive rehabilitation approaches. NEW! More Thought questions in each chapter help you apply concepts to clinical situations. Additional content on evidence-based practice includes systematic reviews and meta-analyses relating to the efficacy and effectiveness of specific treatment approaches. Additional graphics, clinical photographs, and tables depict key information and concepts.
This book explores the long-term outcomes of severe and ongoing trauma-particularly complex posttraumatic stress disorder (C-PTSD)-from phenomenological and cognitive perspectives. For example, C-PTSD can result in impairments at the body-schema level. In order to survive, trauma victims may conduct their lives at the body-image level, thus producing a mismatch between body schema and body image. In turn, as in the case of somatoparaphrenia and body integrity identity disorder, this incongruity can result in body disownership, which will affect long-term outcomes of severe and ongoing trauma.
Eating disorder, also known as ED, is associated with a distorted self-image and abusive relationship. This disease affects self-esteem and emotional well-being. Eating disorders are not entirely about food. Other factors we take for granted play a considerable role during this period leading to a massive uptake or total cut off from food. For anyone dealing with an eating disorder, this book should be your first stop for instant help. With vast clinical expertise and compassion, Jason B. Tiller has provided a walk-through for readers to hasten eating disorder recovery process, including therapies and support details that will help get rid of fear when it comes to embracing change. It also contains the motivation needed to stay above guilt and fear of starting anew. The concept of self-disclosure outlined in this book has not yet been seen in other eating disorder books.
This thesis covers various facets of brain image computing methods and illustrates the scientific understanding of neurodegenerative disorders based on four general aspects of multimodal neuroimaging computing: neuroimaging data pre-processing, brain feature modeling, pathological pattern analysis, and translational model development. It demonstrates how multimodal neuroimaging computing techniques can be integrated and applied to neurodegenerative disease research and management, highlighting relevant examples and case studies. Readers will also discover a number of interesting extension topics in longitudinal neuroimaging studies, subject-centered analysis, and the brain connectome. As such, the book will benefit all health informatics postgraduates, neuroscience researchers, neurology and psychiatry practitioners, and policymakers who are interested in medical image computing and computer-assisted interventions. Sidong Liu received his Bachelor Degree in Bioinformatics from Harbin Institute of Technology (HIT) in 2007. He then obtained a Master of Applied Science with a major in Bioinformatics in 2009, and a Master of IT with a major in Computer Science at the University of Sydney. He conducted his PhD study with a focus on medical image computing in the Biomedical and Multimedia Information Technology(BMIT) Research Group at the School of Information Technologies, the University of Sydney. During his PhD study, supported by an Australian Postgraduate Award (APA), Australia Alzheimers Disease Research Foundation (AADRF) Top-up Scholarship and Australia Sydney University Graduates Union North America (SUGUNA) Travel Grant, he spent one year at the Surgical Planning Laboratory (SPL), Harvard Medical School, as a visiting scholar in 2014. He was awarded a PhD Degree in Dec 2015, and his PhD thesis has received the Springer Thesis Award. He is currently a postdoctoral research fellow with School of Information Technologies, the University of Sydney. His research interests include neuroimage computing, computational neuroscience, biomedical and health informatics, machine learning and big data analytics and its applications in biomedicine.
Linda Smolak is Emerita Professor of Psychology at Kenyon College. She has authored, co-authored, or co-edited eight books, including Body Image: A Handbook of Science, Practice, and Prevention (edited with Thomas E. Cash, 2012) and The Prevention of Eating Problems and Eating Disorders: Theory, Research, and Practice (with Michael P. Levine, 2006). An Associate Editor for Body Image: An International Journal of Research , she has also published dozens of research articles and chapters on body image and disordered eating. Michael P. Levine is Emeritus Professor of Psychology at Kenyon College. He is co-editor of Preventing Eating-Related and Weight-Related Disorders: Collaborative Research, Advocacy, and Policy Change (with Gail L. McVey, Nina Piran, & H. Bruce Ferguson, 2012) and co-author of The Prevention of Eating Problems and Eating Disorders: Theory, Research, and Practice (with Linda Smolak, 2006). The 2013 recipient of the Nielsen Award for Lifetime Achievement from the Founders Council of the National Eating Disorders Association, Dr. Levine is also a Fellow of the Academy of Eating Disorders, which awarded him their Meehan-Hartley Award for Leadership in Public Awareness and Advocacy in 2006, and their Research-Practice Partnership Award in 2008.
Eating disorders and body images problems are quite common among athletes, and this may be a pointer to a bad issue that is often overlooked. Eating disorders have been discovered but most times kept a secret in most sports. It may be undiagnosed or concealed merely due to the competitive nature of the games. Athletes may engage in harmful nutritional practices, strict diets or dietary supplements. Purging, restrictive diets and bingeing have devastating impacts on the general well-being of such people. These acts are carried out to improve their performances, but the results may often prove counterproductive. The performance of athletes suffering from eating disorders may spike and then a downhill spiral which leads to further health problems arises. If left untreated or overlooked, it can be life-threatening. Just like these problems are found in the general populace, so it also affects a significant number of athletes. This book aims to bring to the fore simple and easy to practice diagnostic practices for both the athlete, coaches and people around high-performance athletes who are often under significant stress to up their output levels. Are you an athlete with symptoms of an eating disorder and you keeping it under wraps? Are you a mentor, coach, parent or someone with significant influence over an athlete? Get this book now and start the journey towards healing and sustainable performance.